Funding is also being negotiated to expand the facility to allow production of up to 100 million doses for the UK and around the world.
Executive councillor for development and transport Cathy Muldoon said: "This is fantastic news. West Lothian Council along with Scottish Enterprise have been working closely with Valneva over the past three years on their potential expansion in Livingston. This represents an important investment in the sector and will increase confidence that such significant work can be conducted here in West Lothian.
"The fact that a valued local employer is at the heart of the development of a vaccine for COVID-19 is just as pleasing and will hopefully play a positive role in helping to further enhance our local economy."